147 lines
7.8 KiB
Text
147 lines
7.8 KiB
Text
<?xml version="1.0"?>
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<rdf:RDF xmlns="http://purl.obolibrary.org/obo/arg/research.owl#"
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xml:base="http://purl.obolibrary.org/obo/arg/research.owl"
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xmlns:obo="http://purl.obolibrary.org/obo/"
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xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
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xmlns:vitro="http://vitro.mannlib.cornell.edu/ns/vitro/0.7#"
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xmlns:owl="http://www.w3.org/2002/07/owl#"
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xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
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xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
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<!--
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///////////////////////////////////////////////////////////////////////////////////////
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//
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// Annotation properties
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//
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///////////////////////////////////////////////////////////////////////////////////////
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-->
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<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412"/>
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<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000114"/>
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<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119"/>
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<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
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<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000118"/>
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<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000111"/>
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<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000112"/>
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<!--
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///////////////////////////////////////////////////////////////////////////////////////
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//
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// Datatypes
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//
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///////////////////////////////////////////////////////////////////////////////////////
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-->
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<!--
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///////////////////////////////////////////////////////////////////////////////////////
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//
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// Classes
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//
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///////////////////////////////////////////////////////////////////////////////////////
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-->
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<!-- http://purl.obolibrary.org/obo/BFO_0000034 -->
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<owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
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<!-- http://purl.obolibrary.org/obo/ERO_0000016 -->
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<owl:Class rdf:about="http://purl.obolibrary.org/obo/ERO_0000016"/>
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<!-- http://purl.obolibrary.org/obo/OBI_0500000 -->
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<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500000">
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<rdfs:label xml:lang="en">study design</rdfs:label>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A study design is a plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution.</obo:IAO_0000115>
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<obo:IAO_0000111 xml:lang="en">study design</obo:IAO_0000111>
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<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
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</owl:Class>
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<!-- http://vivoweb.org/ontology/core#Equipment -->
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<owl:Class rdf:about="http://vivoweb.org/ontology/core#Equipment">
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<rdfs:label xml:lang="en">equipment</rdfs:label>
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<obo:IAO_0000112 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A network server is one example. Medical schools and research laboratories can list professional equipment, such as microscopes.</obo:IAO_0000112>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A physical object provided for specific purpose, task or occupation. </obo:IAO_0000115>
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<obo:IAO_0000112 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">server; Bruker Vector-33 FT-IR</obo:IAO_0000112>
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</owl:Class>
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<!-- http://vivoweb.org/ontology/scientific-research#Phase0ClinicalTrial -->
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<owl:Class rdf:about="http://vivoweb.org/ontology/scientific-research#Phase0ClinicalTrial">
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<rdfs:label xml:lang="en">phase 0 clinical trial</rdfs:label>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ERO_0000016"/>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 0 Clinical Trial</obo:IAO_0000115>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 0 is a recent designation for exploratory, first-in-human trials conducted in accordance with the United States Food and Drug Administration's (FDA) 2006 Guidance on Exploratory Investigational New Drug (IND) Studies. Phase 0 trials are also known as human microdosing studies and are designed to speed up the development of promising drugs or imaging agents by establishing very early on whether the drug or agent behaves in human subjects as was expected from preclinical studies.</obo:IAO_0000115>
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</owl:Class>
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<!-- http://vivoweb.org/ontology/scientific-research#Phase1ClinicalTrial -->
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<owl:Class rdf:about="http://vivoweb.org/ontology/scientific-research#Phase1ClinicalTrial">
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<rdfs:label xml:lang="en">phase 1 clinical trial</rdfs:label>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ERO_0000016"/>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">In Phase I trials, researchers test an experimental drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects</obo:IAO_0000115>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 1 Clinical Trial</obo:IAO_0000115>
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</owl:Class>
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<!-- http://vivoweb.org/ontology/scientific-research#Phase2ClinicalTrial -->
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<owl:Class rdf:about="http://vivoweb.org/ontology/scientific-research#Phase2ClinicalTrial">
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<rdfs:label xml:lang="en">phase 2 clinical trial</rdfs:label>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ERO_0000016"/>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">In Phase 2 trials, an experimental study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.</obo:IAO_0000115>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 2 Clinical Trial</obo:IAO_0000115>
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</owl:Class>
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<!-- http://vivoweb.org/ontology/scientific-research#Phase3ClinicalTrial -->
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<owl:Class rdf:about="http://vivoweb.org/ontology/scientific-research#Phase3ClinicalTrial">
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<rdfs:label xml:lang="en">phase 3 clinical trial</rdfs:label>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ERO_0000016"/>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">In Phase 3 trials, an experimental study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the experimental drug or treatment to be used safely.
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</obo:IAO_0000115>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 3 Clinical Trial</obo:IAO_0000115>
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</owl:Class>
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<!-- http://vivoweb.org/ontology/scientific-research#Phase4ClinicalTrial -->
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<owl:Class rdf:about="http://vivoweb.org/ontology/scientific-research#Phase4ClinicalTrial">
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<rdfs:label xml:lang="en">phase 4 clinical trial</rdfs:label>
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<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ERO_0000016"/>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">In Phase 4 trials, post marketing studies delineate additional information including the drug's or treatment's risks, benefits, and optimal use.</obo:IAO_0000115>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 4 Clinical Trial</obo:IAO_0000115>
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</owl:Class>
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</rdf:RDF>
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<!-- Generated by the OWL API (version 3.3.1957) http://owlapi.sourceforge.net -->
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