141 lines
14 KiB
Text
141 lines
14 KiB
Text
<rdf:RDF
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xmlns:j.0="http://aims.fao.org/aos/geopolitical.owl#"
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xmlns:dc="http://purl.org/dc/elements/1.1/"
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xmlns:j.1="http://www.w3.org/2006/12/owl2-xml#"
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xmlns:scirr="http://vivoweb.org/ontology/scientific-research-resource#"
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xmlns:vitro="http://vitro.mannlib.cornell.edu/ns/vitro/0.7#"
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xmlns:j.2="http://purl.org/vocab/vann/"
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xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
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xmlns:j.3="http://www.w3.org/2008/05/skos#"
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xmlns:afn="http://jena.hpl.hp.com/ARQ/function#"
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xmlns:j.4="http://www.w3.org/2003/06/sw-vocab-status/ns#"
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xmlns:owl="http://www.w3.org/2002/07/owl#"
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xmlns:j.5="http://purl.org/dc/terms/"
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xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
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xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" >
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#Instrument">
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<rdfs:subClassOf rdf:resource="http://vivoweb.org/ontology/core#Equipment"/>
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<vitro:shortDef rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An implement used to facilitate work, especially precision work.</vitro:shortDef>
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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<rdfs:subClassOf rdf:nodeID="A0"/>
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An implement used to facilitate work, especially precision work.</vitro:descriptionAnnot>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#Protocol">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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<rdfs:subClassOf rdf:resource="http://purl.org/ontology/bibo/Document"/>
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A protocol is a plan specification which has sufficient level of detail and quantitative information to communicate it between domain experts, so that different domain experts will reliably be able to independently reproduce the process.</vitro:descriptionAnnot>
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<vitro:shortDef rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A plan specification that allows different domain experts to reliably and independently reproduce a process.</vitro:shortDef>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Ontology"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#Phase2ClinicalTrial">
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">In Phase 2 trials, an experimental study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.</vitro:descriptionAnnot>
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<vitro:shortDef rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 2 Clinical Trial</vitro:shortDef>
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<rdfs:subClassOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#ClinicalTrial"/>
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#ClinicalTrial">
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A clinical trial is a research study using human volunteers to answer questions about treatments for diseases and conditions. Clinical trials are conducted in phases. The trials at each phase have a different purpose and help scientists answer different questions.</vitro:descriptionAnnot>
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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<rdfs:subClassOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#ResearchProject"/>
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<vitro:shortDef rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A research study using human volunteers to answer specifc health-related questions. </vitro:shortDef>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#Phase0ClinicalTrial">
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 0 is a recent designation for exploratory, first-in-human trials conducted in accordance with the United States Food and Drug Administration's (FDA) 2006 Guidance on Exploratory Investigational New Drug (IND) Studies. Phase 0 trials are also known as human microdosing studies and are designed to speed up the development of promising drugs or imaging agents by establishing very early on whether the drug or agent behaves in human subjects as was expected from preclinical studies.</vitro:descriptionAnnot>
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<vitro:shortDef rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 0 Clinical Trial</vitro:shortDef>
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<rdfs:subClassOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#ClinicalTrial"/>
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#Phase1ClinicalTrial">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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<rdfs:subClassOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#ClinicalTrial"/>
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">In Phase I trials, researchers test an experimental drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects</vitro:descriptionAnnot>
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<vitro:shortDef rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 1 Clinical Trial</vitro:shortDef>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#providesAccessTo">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#ObjectProperty"/>
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<rdfs:domain rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#AccessService"/>
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<owl:inverseOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#accessProvidedBy"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#ResearchProject">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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<rdfs:subClassOf rdf:resource="http://vivoweb.org/ontology/core#Project"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#StorageService">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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<rdfs:subClassOf rdf:resource="http://vivoweb.org/ontology/core#Service"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#hasDocumentation">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#ObjectProperty"/>
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<rdfs:range rdf:resource="http://purl.org/ontology/bibo/Document"/>
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<owl:inverseOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#documentationFor"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#studyPopulationCount">
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<rdfs:domain rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#ClinicalTrial"/>
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">number of human participants in the study (trial).</vitro:descriptionAnnot>
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#DatatypeProperty"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#Phase4ClinicalTrial">
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<rdfs:subClassOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#ClinicalTrial"/>
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">In Phase 4 trials, post marketing studies delineate additional information including the drug's or treatment's risks, benefits, and optimal use.</vitro:descriptionAnnot>
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<vitro:shortDef rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 4 Clinical Trial</vitro:shortDef>
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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</rdf:Description>
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<rdf:Description rdf:nodeID="A0">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Restriction"/>
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<owl:onProperty rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#hasDocumentation"/>
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<owl:allValuesFrom rdf:resource="http://purl.org/ontology/bibo/Document"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#protocolRealizedBy">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#ObjectProperty"/>
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<rdfs:range rdf:resource="http://vivoweb.org/ontology/core#Service"/>
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<rdfs:domain rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#Protocol"/>
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<owl:inverseOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#realizesProtocol"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#Phase3ClinicalTrial">
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<rdfs:subClassOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#ClinicalTrial"/>
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<vitro:shortDef rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase 3 Clinical Trial</vitro:shortDef>
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">In Phase 3 trials, an experimental study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the experimental drug or treatment to be used safely.
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</vitro:descriptionAnnot>
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#irbNumber">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#DatatypeProperty"/>
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Every clinical trial in the United States must be approved and monitored by an Institutional Review Board (IRB). An IRB is an independent committee of physicians, statisticians, community advocates and others whose objective is to ensure that a clinical trial is ethical and the rights of study participants are protected. </vitro:descriptionAnnot>
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<rdfs:domain rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#ClinicalTrial"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#documentationFor">
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<owl:inverseOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#hasDocumentation"/>
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<rdfs:domain rdf:resource="http://purl.org/ontology/bibo/Document"/>
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#ObjectProperty"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#AccessService">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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<rdfs:subClassOf rdf:resource="http://vivoweb.org/ontology/core#Service"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#accessProvidedBy">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#ObjectProperty"/>
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<rdfs:range rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#AccessService"/>
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<owl:inverseOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#providesAccessTo"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#nctId">
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<rdfs:domain rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#ClinicalTrial"/>
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#DatatypeProperty"/>
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ClinicalTrials.gov is an ICMJE-acceptable public registry, offering up-to-date information for locating clinical trials for a wide range of diseases and conditions. The U.S. National Institutes of Health (NIH), through its National Library of Medicine (NLM), developed this site in collaboration with the Food and Drug Administration (FDA), as a result of the FDA Modernization Act, which was passed into law in November 1997.</vitro:descriptionAnnot>
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<rdfs:subPropertyOf rdf:resource="http://vivoweb.org/ontology/core#identifier"/>
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<vitro:exampleAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCT00000419</vitro:exampleAnnot>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#realizesProtocol">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#ObjectProperty"/>
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<rdfs:domain rdf:resource="http://vivoweb.org/ontology/core#Service"/>
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<rdfs:range rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#Protocol"/>
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<owl:inverseOf rdf:resource="http://vivoweb.org/ontology/scientific-research-resource#protocolRealizedBy"/>
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</rdf:Description>
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<rdf:Description rdf:about="http://vivoweb.org/ontology/scientific-research-resource#ProductionService">
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<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#Class"/>
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<vitro:descriptionAnnot rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A service that produces a physical object or data, such as a custom micro-array chip, a made to order antibody, or a behavioral dataset</vitro:descriptionAnnot>
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<rdfs:subClassOf rdf:resource="http://vivoweb.org/ontology/core#Service"/>
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<vitro:shortDef rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A service that produces a physical object or data.</vitro:shortDef>
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</rdf:Description>
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</rdf:RDF>
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