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brianjlowe 2013-10-03 16:38:24 -04:00
parent 601a0674ab
commit e21b3e7077
31 changed files with 3300 additions and 889 deletions
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rdf/tbox/filegraph/clinical.owl
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@ -98,7 +98,7 @@
<!-- http://purl.obolibrary.org/obo/ERO_0000015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/ERO_0000015">
<rdfs:label xml:lang="en">human study</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ERO_0000014"/>
<obo:IAO_0000112 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A clinical trial.</obo:IAO_0000112>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OCRe</obo:IAO_0000119>
@ -114,7 +114,7 @@
<!-- http://purl.obolibrary.org/obo/ERO_0000016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/ERO_0000016">
<rdfs:label xml:lang="en">clinical trial</rdfs:label>
<owl:equivalentClass>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
@ -137,7 +137,7 @@
<owl:Class rdf:about="http://purl.org/net/OCRe/study_design.owl#OCRE100038">
<rdfs:label xml:lang="en">phase (ocre)</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phase describes the level of a trial required of drugs before (and after) they are routinely used in clinical practice:
- Phase I trials assess toxic effects on humans (not many people participate in them, and usually without controls);
@ -155,7 +155,7 @@ The concept of phase is not applicable to trials studying certain interventions
<!-- http://purl.org/net/OCRe/study_design.owl#Phase_0 -->
<owl:Class rdf:about="http://purl.org/net/OCRe/study_design.owl#Phase_0">
<rdfs:label xml:lang="en">phase 0</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/net/OCRe/study_design.owl#OCRE100038"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A Phase 0 trial is an exploratory trial involving very limited human exposure, with no therapeutic or diagnostic intent (e.g., screening study, microdose study). [http://prsinfo.clinicaltrials.gov/definitions.html]</obo:IAO_0000115>
<statistics:curator rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Simona</statistics:curator>
@ -166,7 +166,7 @@ The concept of phase is not applicable to trials studying certain interventions
<!-- http://purl.org/net/OCRe/study_design.owl#Phase_1 -->
<owl:Class rdf:about="http://purl.org/net/OCRe/study_design.owl#Phase_1">
<rdfs:label xml:lang="en">phase 1</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/net/OCRe/study_design.owl#OCRE100038"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A Phase I trial assesses toxic effects on humans (not many people participate, and usually without controls) [Glossary of Terms in The Cochrane Collaboration]</obo:IAO_0000115>
<statistics:curator rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Simona</statistics:curator>
@ -177,7 +177,7 @@ The concept of phase is not applicable to trials studying certain interventions
<!-- http://purl.org/net/OCRe/study_design.owl#Phase_2 -->
<owl:Class rdf:about="http://purl.org/net/OCRe/study_design.owl#Phase_2">
<rdfs:label xml:lang="en">phase 2</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/net/OCRe/study_design.owl#OCRE100038"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A Phase ll trial assesses therapeutic benefit (usually involving a few hundred people, usually with controls, but not always) [Glossary of Terms in The Cochrane Collaboration]</obo:IAO_0000115>
<statistics:curator rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Simona</statistics:curator>
@ -188,7 +188,7 @@ The concept of phase is not applicable to trials studying certain interventions
<!-- http://purl.org/net/OCRe/study_design.owl#Phase_3 -->
<owl:Class rdf:about="http://purl.org/net/OCRe/study_design.owl#Phase_3">
<rdfs:label xml:lang="en">phase 3</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/net/OCRe/study_design.owl#OCRE100038"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A Phase III trial compares the new treatment against standard (or placebo) treatment (usually a full
randomised controlled trial). At this point, a drug can be approved for community use. [Glossary of Terms in The Cochrane Collaboration]</obo:IAO_0000115>
@ -200,7 +200,7 @@ randomised controlled trial). At this point, a drug can be approved for communit
<!-- http://purl.org/net/OCRe/study_design.owl#Phase_4 -->
<owl:Class rdf:about="http://purl.org/net/OCRe/study_design.owl#Phase_4">
<rdfs:label xml:lang="en">phase 4</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/net/OCRe/study_design.owl#OCRE100038"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A Phase IV study monitors a new treatment in the community, often to evaluate longterm safety and effectiveness. [Glossary of Terms in The Cochrane Collaboration]</obo:IAO_0000115>
<statistics:curator rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Simona</statistics:curator>
@ -211,7 +211,7 @@ randomised controlled trial). At this point, a drug can be approved for communit
<!-- http://purl.org/net/OCRe/study_design.owl#Single_group_study -->
<owl:Class rdf:about="http://purl.org/net/OCRe/study_design.owl#Single_group_study">
<rdfs:label xml:lang="en">single group study</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/net/OCRe/research.owl#Interventional_study"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A single group study is an interventional study that has only a single allocation group and no contemporaneuos comparison group.
A study in which an individual acts has his/her own comparison does not fall into this category, since an individual is not a group.</obo:IAO_0000115>
@ -224,7 +224,7 @@ A study in which an individual acts has his/her own comparison does not fall int
<!-- http://vivoweb.org/ontology/core#ClinicalRole -->
<owl:Class rdf:about="http://vivoweb.org/ontology/core#ClinicalRole">
<rdfs:label xml:lang="en">clinical role</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A role of observing or treating patients</obo:IAO_0000115>
</owl:Class>